产品介绍：
产品说明
应用
Microsomes from Liver, Pooled has been used to measure the in vitro stabilities of the prodrugs. It has also been used in microsomal incubation to generate BTX-3 metabolites to serve as references for liquid chromatography with tandem mass spectrometry (LC-MS/MS) analyses of urine.
生化/生理作用
Microsomal cytochrome P450 proteins can catalyze the transfer of a single oxygen atom to endogenous and exogenous compounds, like steroids and phenobarbital, meant for excretion and detoxification.
肝微粒体是来源于肝细胞内质网的亚细胞颗粒。这些微粒体是药物代谢酶(包括细胞色素 P-450)的丰富来源。不同来源的微粒体池有助于研究外源代谢和药物相互作用。
单位定义
One unit will produce 1.0 picomole of 6 beta-hydroxytestosterone per minute at pH 7.4 at 37 deg C.
产品性质
| 质量水平 | 200 |
| 生物来源 | Monkey (Cynomolgus spp.) |
| 测定 | ~10 mg per vial |
| 形式 | liquid |
| specific activity | ≥5000 units/mg protein |
| 运输 | dry ice |
| 储存温度 | −70℃ |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
