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α1-Antichymotrypsin from human plasma

α1-Antichymotrypsin 来源于人类血浆

品牌
Sigma-Aldrich
CAS
141176-92-3
货号
A9285
规格纯度
≥92.5% (SDS-PAGE), lyophilized powder
参考价格
2195.59 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

α1-Antichymotrypsin (α1-ACT) is also known as serpin peptidase inhibitor, clade A member 3 (SERPINA3). It is a 68 kDa serine protease inhibitor, secreted by the liver. It belongs to the serpin superfamily of protease inhibitors. SERPINA3 is located on human chromosome 14q32.1.

应用

α1-Antichymotrypsin from human plasma has been used as a component in yeast extract peptone dextrose broth (YEPD) for biofilm dispersion assays.

生化/生理作用

α1-Antichymotrypsin (α1-ACT) can block the functions of various serine proteases like chymotrypsin and cathepsin G. It serves as a potential therapeutic target of endometrial carcinoma (EC).
Specific inhibitor of chymotrypsin-like serine proteases. Promotes amyloid-β polymerization in vitro and in vivo. Levels in plasma and cerebrospinal fluid have been found to correlate with progression of dementia in Alzheimer′s patients and induce phosphorylation of tau protein in neurons.

包装

Package size based on protein content.

外形

Lyophilized powder containing Tris buffer salt and NaCl.

基本信息

MDL编号MFCD00162030

产品性质

质量水平200
生物来源human plasma
测定≥92.5% (SDS-PAGE)
形式lyophilized powder
分子量 55-66 kDa
technique(s)microbiological culture: suitable
UniProt登记号P01011
储存温度−20℃
Gene Informationhuman ... SERPINA3(12)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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