产品说明
应用
Lee, et al,. reported a non-radioactive version of in vitro phosphorylation where γ-[(Propargyl)-imido]-ATP (compound 1) was successfully used instead of γ-32P-modified ATP to phosphorylate GST-tagged recombinant p27kip1 with protein kinase cdk2. The phosphorylated, alkyne-modified protein substrate can be labeled with azides of biotin or fluorescent dyes using Cu(I)-catalyzed click chemistry.
包装
1 mg in glass bottle
法律信息
The purchase of this product for use in applications relating to copper catalyzed azide-alkyne cycloaddition chemistry ("Click Chemistry") includes a limited, nontransferable license to intellectual property owned by The Scripps Research Institute to use this product solely for internal non-commercial research activities and specifically excludes clinical, therapeutic, or diagnostic use in humans or animals and manufacturing purposes. Information regarding a license for commercial use in Click Chemistry may be obtained directly from The Scripps Research Institute, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, or by contacting 858-784-8140 or click@scripps.edu.
基本信息
| 经验(实验)分子式 | C13H19N6O12P3 · xNa+ |
| 分子量 | 544.24 (free acid basis) |
| PubChem化学物质编号 | 329769104 |
| NACRES | NA.22 |
产品性质
| 质量水平 | 200 |
| 测定 | ≥95% (HPLC) |
| 形式 | solid |
| reaction suitability | reaction type: click chemistry |
| 溶解性 | 10 mM Tris-HCl, pH 7.5: soluble |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| SMILES string | NC1=NC=NC2=C1N=CN2[C@H]3O[C@H](COP(OP(O)(OP(O)(NCC#C)=O)=O)(O)=O)[C@@H](O)[C@H]3O |
| InChI | 1S/C13H19N6O12P3/c1-2-3-18-32(22,23)30-34(26,27)31-33(24,25)28-4-7-9(20)10(21)13(29-7)19-6-17-8-11(14)15-5-16-12(8)19/h1,5-7,9-10,13,20-21H,3-4H2,(H,24,25)(H,26,27)(H2,14,15,16)(H2,18,22,23)/t7-,9-,10-,13?/m1/s1 |
| InChI key | PIPOEUYSJJTELD-RJNFYWFKSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
