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Platelet Membrane Glycoproteins, IIbIIIa, Human Platelets

品牌
Sigma-Aldrich
货号
528240
包装型号
规格纯度
参考价格
8352.96 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Native, platelet membrane glycoprotein IIbIIIaA from human platelets. A platelet integrin that binds to fibrinogen via the recognition sequence Arg-Gly-Asp-Ser. Acts as a receptor for such adhesive ligands as fibrinogen, fibronectin and von Willebrand factor during platelet stimulation. Glycoproteins IIb and IIIa constitute the fibrinogen receptor and are required for platelet aggregation. Glycoprotein IIb consists of two disulfide-linked subunits, GPIIbα and GPIIbβ, whereas GPIIIa has only one polypeptide chain.
Native, platelet membrane glycoprotein IIbIIIaA from human platelets. A platelet integrin that binds fibrinogen via the recognition sequence Arg-Gly-Asp-Ser. Acts as a receptor for such adhesive ligands as fibrinogen, fibronectin and von Willebrand factor during platelet stimulation. Glycoproteins IIb and IIIa constitute the fibrinogen receptor and are required for platelet aggregation. Glycoprotein IIb consists of two disulfide-linked subunits, GPIIbα and GPIIbβ, whereas GPIIIa has only one polypeptide chain.

包装

1 mg in Plastic ampoule
Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

外形

In 100 mM NaCl, 20 mM Tris-HCl, 1 mM CaCl2, 50% glycerol, ≤0.1% sodium azide, pH 7.4.

制备说明

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

重悬

Following initial thaw, aliquot and freeze (-70°C). Avoid freeze/thaw cycles.

其他说明

Schwarz M., et al. 2004. J. Pharmacol. Exp. Therap.308, 1002.
Wippler, J., et al. 1994. J. Biol. Chem. 269, 8754.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

产品性质

形式liquid
质量水平100
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
运输wet ice
储存温度−70℃

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1

Sigma-Aldrich

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