产品说明
一般描述
A potent and selective inhibitor of poly(ADP-ribose) polymerase (PARP; IC50 = 40 nM). Significantly reduces infarcet volume in rat focual cerebrale ischemia model.
A very potent and selective poly(ADP-ribose)polymerase (PARP) inhibitor (IC50 = 40 nM). Significantly reduces infarcet volume in rat focual cerebrale ischemia model.
包装
1 mg in Plastic ampoule
生化/生理作用
Product does not compete with ATP.
Reversible: no
Cell permeable: no
警告
Toxicity: Harmful (C)
其他说明
Eliasson, M.J., et al. 1997. Nat. Med. 3, 1089.
Takahashi, K., et al. 1997. J. Cereb. Blood Flow Metabl. 17, 1137.
Suto, M.J., et al. 1991. Anticancer Drug Des. 6, 107.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
经验(实验)分子式 | C18H26N2O2 |
分子量 | 302.41 |
MDL编号 | MFCD01866274 |
产品性质
质量水平 | 100 |
测定 | ≥90% (HPLC) |
形式 | solid |
效能 | 40 nM IC50 |
manufacturer/tradename | Calbiochem® |
储存条件 | OK to freeze |
颜色 | off-white |
溶解性 | DMSO: 5 mg/mL |
运输 | ambient |
储存温度 | −20℃ |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |