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Monoclonal Anti-RNF19 antibody produced in mouse

品牌
Sigma-Aldrich
货号
WH0025897M1
规格纯度
clone 4E4, ascites fluid
参考价格
4888.5 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson′s disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported. (provided by RefSeq)

免疫原

RNF19 (NP_056250, 739 a.a. ~ 837 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MKTSCSHGSSDYHTRFATVNILPEVENDRLENSPHQCSISVVTQTASCSEVSQLNHIAEEHGNNGIKPNVDLYFGDALKETNNNHSHQTMELKVAIQTE

外形

Solution

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

基本信息

NACRESNA.41

产品性质

质量水平100
生物来源mouse
偶联物unconjugated
抗体形式ascites fluid
antibody product typeprimary antibodies
克隆4E4, monoclonal
species reactivityhuman
technique(s)indirect ELISA: suitable
western blot: 1:500-1:1000
同位素/亚型IgMκ
GenBank® accession no.NM_015435
UniProt登记号Q9NV58
运输dry ice
储存温度−20℃
Gene Informationhuman ... RNF19A(25897)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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