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Monoclonal Anti-GMNN antibody produced in mouse

品牌
Sigma-Aldrich
货号
WH0051053M1
规格纯度
clone 1A8, purified immunoglobulin, buffered aqueous solution
参考价格
4474.51 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Geminin (GMNN) is a nuclear regulator protein encoded by GMNN gene. This gene is located on human chromosome 6p22.3. It is expressed in the the cell cycle during S, G2 and M phases.

免疫原

GMNN (AAH05185, 110 a.a. ~ 209 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LYEALKENEKLHKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEETVEDSLVEDSEIGTCAEGTVSSSTDAKPCI

生化/生理作用

Geminin (GMNN) prevents replication of DNA. It participates in cancer pathophysiology and developmental process. This protein also participates in several stages of development like pre-implantation, germ layer formation, cell commitment and specification. It also has roles in the maintenance of genome integrity at mid blastula transition, epithelial to mesenchymal transition during gastrulation, neural development, organogenesis and axis patterning. GMNN controls chromatin remodeling.

外形

Solution in phosphate buffered saline, pH 7.4

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

产品性质

质量水平100
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆1A8, monoclonal
形式buffered aqueous solution
species reactivityhuman
technique(s)immunofluorescence: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
indirect ELISA: suitable
western blot: 1-5 μg/mL
同位素/亚型IgG1κ
GenBank® accession no.BC005185
UniProt登记号O75496
运输dry ice
储存温度−20℃
Gene Informationhuman ... GMNN(51053)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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