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Monoclonal Anti-CD5L antibody produced in mouse

品牌
Sigma-Aldrich
货号
WH0000922M1
规格纯度
clone 1C8, purified immunoglobulin, buffered aqueous solution
参考价格
4474.51 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

CD5 molecule like (CD5L), also known as apoptosis inhibitor of macrophage (AIM), is encoded by the gene mapped to human chromosome 1q23.1. CD5L is a member of the scavenger receptor cysteine-rich (SRCR) superfamily. It is a soluble protein expressed generally by macrophages in lymphoid and inflamed tissues. This protein is characterized with a potential region of O-linked glycosylation in a Pro-Ser-Thr-rich polypeptide, separating SRCR domains 1 and 2.

免疫原

CD5L (AAH33586, 41 a.a. ~ 140 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
QKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPAEKEQKVLIQSVSCTGTEDTLAQCEQEEVYDCSHDEDAGASCENPESSFSPVPEGVRL

生化/生理作用

CD5 molecule like (CD5L) controls lipid metabolism and regulates T-helper (Th) 17 cell pathogenicity. In addition, it also has an ability to regulate leukocyte migration and inflammatory responses. Overexpression of the protein has been observed in atopic dermatitis (AD) patients. Thus, it can be used as a potential biomarker for AD.

外形

Solution in phosphate buffered saline, pH 7.4

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

基本信息

NACRESNA.41

产品性质

质量水平100
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆1C8, monoclonal
形式buffered aqueous solution
species reactivityhuman
technique(s)immunoprecipitation (IP): suitable
indirect ELISA: suitable
western blot: 1-5 μg/mL
同位素/亚型IgG2aκ
GenBank® accession no.BC033586
UniProt登记号O43866
运输dry ice
储存温度−20℃
Gene Informationhuman ... CD5L(922)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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