产品介绍:
产品说明
一般描述
EMPROVE® ESSENTIAL DAB,USP
生化/生理作用
L-谷氨酰胺是一种必需氨基酸,作为细胞培养过程中主要的能量来源而成为培养基的重要组分。L-谷氨酰胺在干粉及冷冻溶液的状态下极为稳定。然而,L-谷氨酰胺在液体培养基或储存溶液中均会相对较快的降解。最佳的细胞表现通常需要在使用前向培养基中添加L-谷氨酰胺补充剂。
分析说明
Assay (perchloric acid titration, calculated on dried substance) | 99.0 - 101.0 % |
Identity (IR-spectrum) | passes test |
Appearance | white to almost white, fine powder |
Appearance of solution (25 g/l; CO₂-free water) | clear and colorless |
Spec. rotation (α 20/D, 100 g/l, hydrochloric acid 2 mol/l, calc. on dried substance) | +31.5 to +33.0 |
Spec. rotation (α 20/D, 40 g/l, water, calc. on dried substance) | +6.3 to +7.3 |
pH (25 g/l; CO₂-free water) | 4.0 - 6.0 |
Chloride (Cl) | ≤ 200 ppm |
Sulfate (SO₄) | ≤ 200 ppm |
Heavy metals (as Pb) | ≤ 10 ppm |
Cu (Copper) | ≤ 25 ppm |
Fe (Iron) | ≤ 10 ppm |
Fe (Iron) (ICP) | ≤ 10 ppm |
Mn (Manganese) | ≤ 25 ppm |
Ni (Nickel) | ≤ 2 ppm |
Zn (Zinc) | ≤ 130 ppm |
NH₄ (Ammonium) | ≤ 0.1 % |
Ninhydrin - positive substances (TLC) | ≤ 0.5 % |
Residual solvents (ICH Q3C) | excluded by manufacturing process |
Sulfated ash (600 °C) | ≤ 0.1 % |
Loss on drying (105 °C; 3 h) | ≤ 0.3 % |
Bacterial endotoxins | ≤ 2.0 I.U./g |
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*). |
Corresponds to DAB, USP |
法律信息
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
线性分子式 | H2NCOCH2CH2CH(NH2)CO2H |
分子量 | 146.14 |
Beilstein | 1723797 |
MDL编号 | MFCD00008044 |
EC索引号 | 200-292-1 |
产品性质
质量水平 | 500 |
agency | DAB USP |
产品线 | EMPROVE® ESSENTIAL |
效能 | 7500 mg/kg LD50, oral (Rat) |
pH值(酸碱度) | 4.0-6.0 (20 ℃, 25 g/L in H2O) |
mp | 185 ℃ (dec.) (lit.) |
溶解性 | 100 g/L |
密度 | 1.47 g/cm3 at 20 ℃ |
堆积密度 | 640 kg/m3 |
储存温度 | 2-30℃ |
SMILES string | N[C@@H](CCC(N)=O)C(O)=O |
InChI | 1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1 |
InChI key | ZDXPYRJPNDTMRX-VKHMYHEASA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |