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PAX-2 (EP235) Rabbit Monoclonal Primary Antibody

品牌
Sigma-Aldrich
货号
311R-1
包装型号
规格纯度
参考价格
2218.68 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

PAX-2 is a homeogene strongly expressed during kidney development. PAX-2 gene is expressed in the metanephric mesenchyma after ureter bud induction and is a key factor for the mesenchyma-epithelium conversion. Animals transgenic for PAX-2 have severe renal abnormalities and cysts but no solid tumoral features. The oncogenic potential of the PAX gene family has been reported <em>in vitro</em> with transformation of cell cultures and <em>in vivo</em> with cell injections in nude mice. Gnarra et al. showed PAX-2 expression in renal carcinoma cell lines and underlined its potential role in cell proliferation in these lines.1 Mazal et al. demonstrated PAX-2 nuclear expression in 88% of clear cell renal cell carcinomas as well as 18% of papillary renal cell carcinoma, and 13% of chromophobe renal cell carcinomas.2 More recently, Chivukula et al. demonstrated utility in distinguishing ovarian serous papillary carcinoma (anti-PAX-2 positive) from breast carcinoma (anti-PAX-2 negative).3

质量


IVD

IVD

IVD

RUO

联系

PAX-2 Positive Control Slides, Product No. 311S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

制备说明

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其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of sigma-aldrich Co. LLC

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平500
100
偶联物unconjugated
抗体形式culture supernatant
antibody product typeprimary antibodies
克隆EP235, monoclonal
描述 (For In Vitro Diagnostic Use in Select Regions (See Chart))
形式buffered aqueous solution
species reactivityhuman
包装bottle of 1.0 mL predilute (311R-17)
bottle of 7.0 mL predilute (311R-18)
vial of 0.1 mL concentrate (311R-14)
vial of 0.5 mL concentrate (311R-15)
vial of 1.0 mL concentrate (311R-16)
manufacturer/tradenameCell Marque
technique(s)immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:10-1:50
同位素/亚型IgG
运输wet ice
储存温度2-8℃

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