SATB2 (EP281) Rabbit Monoclonal Primary Antibody

产品说明

一般描述

Special AT-rich sequence-binding protein 2 (SATB2) is a recently described marker that functions as a nuclear matrix-associated transcription factor. It has been reported that SATB2, in combination with CK20, could identify almost all colorectal carcinomas,¹ including poorly differentiated colorectal carcinomas.² Upper gastrointestinal (GI) carcinomas and pancreatic ductal carcinomas are usually negative for SATB2,¹ and ovarian carcinomas, lung adenocarcinomas, and adenocarcinomas from other origin are rarely positive for SATB2.^1,2 Therefore, SATB2 is a good marker for identifying a carcinoma of colorectal origin when working on a tumor of unknown primary.^1,2,5 Another potential utility of SATB2 is to identify neuroendocrine neoplasms/carcinomas of the left colon and rectum because SATB2 is usually negative in other neuroendocrine neoplasms of the GI tract, pancreas, and lung.³ More recently, it has been shown in literature that SATB2 is a sensitive marker for tumors with osteoblastic differentiation.⁴

质量

IVD

IVD

IVD

RUO

联系

SATB2 Positive Control Slides, Product No. 384S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

制备说明

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其他说明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律信息

Cell Marque is a trademark of sigma-aldrich Co. LLC

基本信息

产品性质