基本信息
分子式 | C19H23N3O2 |
分子量 | 325.40 |
存储条件 | Freezer -20℃ |
产品描述
NKL 22 is a HDAC inhibitor. The value of IC 50 is 78 uM NKL 22 increase frataxin protein concentrations NKL 22 inhibitors increase FXN mRNA in FRDA lymphocytes. HDAC inhibitors act directly on FXN. [1]
靶点(IC50 & Targe)
HDAC
参考文献
[1]. D Herman et al. Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia. Nat Chem Biol, 2006 Oct, 2(10):551-8.
安全信息
图形或危害标志 | |
提示语 | Warning |
危险说明 | H315 H319 H335 |
防范说明 | P261 P305+P351+P338 P302+P352 |