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2'-Deoxyuridine 5'-monophosphate disodium salt

2'-脱氧尿苷 5'-单磷酸二钠盐

品牌
J&K
CAS
42155-08-8
货号
599098
包装型号
规格纯度
99%
参考价格
1141 *本价格含增值税费
促销
数量
-+
产品介绍:

基本信息

分子式C9H11N2Na2O8P
分子量352.15
MDL编码MFCD00065282
EINECS 编号255-687-1
存储条件Freezer -20℃

一般描述

2′-Deoxyuridine 5′-monophosphate disodium salt (dUMP) is a substrate for thymidylate synthase and is converted to deoxythymidine monophosphate (dTMP).

应用

2′-Deoxyuridine 5′-monophosphate (dUMP) is used by the enzyme thymidylate synthetase (TS) (EC 2.1.1.45) for the de novo production of dTMP. dUMP is used as the reference substrate in studies of dUMP analogues in potential chemotherapy applications.

in ultraperformance liquid chromatography-tandem mass spectrometry (UPLC/MS/MS) assay.to stimulate proliferation of peripheral blood mononuclear cell (PBMCs) exposed to influenza virus antigen.in thymidylate synthase activity assay Helicobacter pylori.

生化/生理作用

2′-Deoxyuridine 5′-monophosphate disodium salt (dUMP) conversion to pyrimidine is inhibited by methotrexate. The inhibition of dUMP to deoxythymidine monophosphate (dTMP) at the methylation step is a key in controlling bacterial and eukaryotic cell growth.

安全信息

图形或危害标志
提示语Warning
危险说明H302
H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
TSCA

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