应用
p-Toluenesulfonylmethyl isocyanide is a synthetic reagent used in the synthesis of triplet drugs with the 1,3,5-trioxazatriquinane skeleton, pyrroles, oxazoles and in imidazoles. It serves as an isonitrile component in a diastereoselective Passerini reaction. Furthermore, it is used in the Van Leusen reaction to convert aldehydes to nitriles.
备注
Moisture, air and light sensitive. Store in cool place. Incompatible with strong bases and strong oxidizing agents.
基本信息
MDL
MFCD00000005
EINECS
253-140-1
分子式
C9H9NO2S
分子量
195.24
熔点
109-114°
灵敏度
Moisture Sensitive. Store under Nitrogen. Ambient temperatures.
形态
Crystalline powder
溶解性
Soluble in chloroform and methanol. Insoluble in water.
Beilstein
3592382
GHS危害和防范说明
GHS符号
Hazard Statements
H300-H311-H331
Fatal if swallowed.Toxic in contact with skin.Toxic if inhaled.
Precautionary Statements
P280h-P309-P310
Wear protective gloves/clothing.IF exposed or if you feel unwell:Immediately call a POISON CENTER or doctor/physician.
安全信息
危险等级
6.1
包装组
II
危险类别
23/24/25
Toxic by inhalation, in contact with skin and if swallowed.
安全等级
36/37-45
Wear suitable protective clothing and gloves.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
TSCA
否
