应用
Quinolinic acid is an endogenous NMDA agonist. Quinolinic acid is a metabolite of tryptophan that acts as a putative NMDA receptor agonist. Quinolinic acid is an ?“excitotoxic?” metabolite and an agonist of N-methyl-D-aspartate receptors. properties of KYNA raise the possibility of a functional link between KYNA and QUIN in the brain which may be of relevance for an understanding of human neurodegenerative disorders. Quinolinic acid is a potent endogenous excitant at amino acid receptors in CNS.
备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
基本信息
MDL
MFCD00006295
EINECS
201-874-8
分子式
C7H5NO4
分子量
167.12
熔点
ca 188° dec.
灵敏度
Ambient temperatures.
形态
Crystalline powder
溶解性
Soluble in water (partly), alkalies, dilute aqueous base, DMSO, and alcohol (slightly).
Beilstein
137110
Merck
14,8073
GHS危害和防范说明
GHS符号
Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
安全信息
危险类别
36/37/38
Irritating to eyes, respiratory system and skin.
安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RTECS
US7967250
TSCA
是
