应用
Phenylhydrazine hydrochloride is used as a selective mannosidase inhibitor. It is used in the study of tyrosine phosphorylation of janus protein tyrosine kinase in the EPO-responsive normal erythroblastoid cells of anemic mice. It is used in steroid assays and as an N-protecting reagent. Its free base, phenylhydrazine is used to prepare indoles, which find application as intermediates in the synthesis of various dyes and pharmaceuticals.
备注
Air and light sensitive. Hygroscopic. Store in cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents and bases.
基本信息
MDL
MFCD00012924
EINECS
200-444-7
分子式
C6H8N2?HCl
分子量
144.61
熔点
ca 252° dec.
灵敏度
Ambient temperatures.
形态
Crystalline powder
溶解性
Soluble in water and alcohol.
Beilstein
3594958
Merck
14,7293
GHS危害和防范说明
GHS符号
Hazard Statements
H301-H311-H331-H315-H319-H317-H341-H350-H372-H400
Toxic if swallowed.Toxic in contact with skin.Toxic if inhaled.Causes skin irritation.Causes serious eye irritation.May cause an allergic skin reaction.Suspected of causing genetic defects.May cause cancer.Causes damage to organs through prolonged or repeated exposure.Very toxic to aquatic life.
Precautionary Statements
P260-P201-P301+P310a-P305+P351+P338-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray.Obtain special instructions before use.Obtain special instructions before use.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
安全信息
危险等级
6.1
包装组
II
危险类别
45-23/24/25-36/38-43-48/23/24/25-68-50
May cause cancer.Toxic by inhalation, in contact with skin and if swallowed.Irritating to eyes and skin.May cause sensitization by skin contact.Toxic: danger of serious damage to health by prolonged exposure through inhalation, in contact with skin and if swallowed.Possible risk of irreversible effects.Very toxic to aquatic organisms.
安全等级
53-45-61
Avoid exposure - obtain special instructions before use.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).Avoid release to the environment. Refer to special instructions/safety data sheets.
欧盟危险品标志
RTECS
MV9000000
TSCA
是