应用
Pentafluorobenzene is a fluorinated benzene with anesthetic properties. Pentafluorobenzene has been shown to potently and reversibly inhibited human α4β2 neuronal nicotinic acetylcholine receptor depe ndent on drug hydrophobicity in Xenopus laevis oocyte. New reaction conditions are described that enable the direct arylation of pentafluorobenzene with sterically encumbered aryl bromides and aryl chlorides. Bis (pentafluoropheny1) methane and tris (pentafluoropheny1) methane were prepared in 77 and 92% yields, respectively, by a Friedel-Crafts reaction of pentafluorobenzene with methylene chloride and chloroform using aluminum chloride as the Lewis acid.

备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

基本信息

MDL
MFCD00000286

EINECS
206-658-7

分子式
C₆HF₅

分子量
168.06

熔点
-48°

沸点
84-85°

闪点
13°(55°F)

密度
1.518

折射率
1.3910

灵敏度
Ambient temperatures.

形态
Liquid

溶解性
Insoluble in water.

Beilstein
1911549

GHS危害和防范说明

GHS符号

Hazard Statements
H225-H302
Highly flammable liquid and vapour.Harmful if swallowed.

Precautionary Statements
P210-P280a-P240-P241-P303+P361+P353-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.Wear protective gloves and eye/face protection.Ground/bond container and receiving equipment.Use explosion-proof electrical/ventilating/lighting/ equipment.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
3

包装组
II

危险类别
11-22
Highly flammable.Harmful if swallowed.

安全等级
16-29-33-36
Keep away from sources of ignition - No smoking.Do not empty into drains.Take precautionary measures against static discharges.Wear suitable protective clothing.

欧盟危险品标志

RTECS
DA6651600

TSCA
是