应用
Nitrofurantoin is a nitrofuran antibiotic that is used as a substrate of bacterial nitrofuran reductase to study the interactions of active metabolites with DNA, ribosomal proteins and metabolic and pro-oxidant processes. It is an antibactericidal compound that has been historically prepared by the reaction of 1-aminohydantoin sulfate and 5-nitro-2-furaldehyde diacetate. It shows activity against many Gram-positive and Gram-negative bacteria. Nitrofurantoin is effective against enterococci, staphylococci, streptococci, corneybacteria, many strains of Escherichia coli.
备注
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Store under dry inert gas. It is hygroscopic in nature. Incompatible with oxidizing agents. It is sensitive to light.
基本信息
MDL
MFCD00003224
EINECS
200-646-5
分子式
C8H6N4O5
分子量
238.16
熔点
ca 265° dec.
灵敏度
Hygroscopic. Light Sensitive. Store under Nitrogen. Ambient temperatures.
形态
Powder
溶解性
Soluble in water (<0.01 g/100 ml at 19°C), dimethyl sulfoxide and methanol.
GHS危害和防范说明
GHS符号
Hazard Statements
H302-H334-H317
Harmful if swallowed.May cause allergy or asthma symptoms or breathing difficulties if inhaled.May cause an allergic skin reaction.
Precautionary Statements
P284-P261-P280g-P304+P340-P342+P311a-P501a
Wear respiratory protection.Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Dispose of contents/container in accordance with local/regional/national/international regulations.
安全信息
危险类别
22-42/43
Harmful if swallowed.May cause sensitization by inhalation and skin contact.
安全等级
22-24-37-45-60
Do not breathe dust.Avoid contact with skin.Avoid contact with skin.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).This material and its container must be disposed of as hazardous waste
欧盟危险品标志
RTECS
MU2800000
TSCA
是
