应用
Nicotinamide is a building block (active component) of coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phopshate (NADP). It may be used as a substrate of nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12), the rate-limiting enzyme for NAD(+) biosynthesis and an important signaling molecule. It is an amide derivative of vitamin B3 and a PARP inhibitor.

备注
Stable under recommended storage conditions. Incompatible with oxidizing agents.

基本信息

MDL
MFCD00006395

EINECS
202-713-4

分子式
C₆H₆N₂O

分子量
122.13

熔点
128-132°

闪点
182°(360°F)

密度
1.40

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Soluble in water, ethanol , glycerol, DMSO , methanol, butanol and chloroform. Slightly soluble in ether.

Beilstein
383619

Merck
14,6523

GHS危害和防范说明

GHS符号

Hazard Statements
H319
Causes serious eye irritation.

Precautionary Statements
P280i-P264-P305+P351+P338-P337+P313
Wear eye/face protection.Wash thoroughly after handling.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.If eye irritation persists: Get medical advice/attention.

安全信息

危险类别
36
Irritating to eyes.

安全等级
26-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

RTECS
QS3675000

TSCA
是