应用
2-Methylcyclopentane-1,3-dione is an efficient synthon for the synthesis of (?±)-α-cuparenone. The alkylation of 2-methylcyclopentane-1,3-dione (A) with 2-(1-naphthyl)ethyl bromide gives only the O-alkylation product. Mixtures of C- and O-alkyl derivatives are obtained. Michael addition of 2-methylcyclopentane-1,3-dione to methyl vinyl ketone in water gives 2-methyl-2-(3-oxo- butyl)-1,3-cyclopentanedione (3), an important intermediate of natural product chemistry. 2-Methylcyclopentane-1, 3-dione is an efficient synthon for the synthesis of (?±)-α-cuparenone.

备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

基本信息

MDL
MFCD00001406

EINECS
212-153-2

分子式
C₆H₈O₂

分子量
112.13

熔点
212-216°

灵敏度
Ambient temperatures.

形态
Powder/crystals

溶解性
Solubility in hot Methanol (almost transparency).

Beilstein
1237255

安全信息

TSCA
否