应用
Methyl 4-aminobenzoate is used in the synthesis of guanidine alkaloids, (?±)-martinelline and (?±)-martinellic acid by a protic acid catalyzed hetero Diels-Alder coupling reaction with N-Cbz 2-pyrroline. It is also used in organic synthesis and acts as a dye intermediate. Further, it is used to prepare 4-(2-methyl-4-oxo-4H-quinazolin-3-yl)-benzoic acid methyl ester by reacting with 2-acetylamino-benzoic acid.
备注
Incompatible with strong oxidizing agents and strong bases.
基本信息
MDL
MFCD00007891
EINECS
210-598-7
分子式
C8H9NO2
分子量
151.17
熔点
110-114°
灵敏度
Ambient temperatures.
形态
Crystalline powder
溶解性
Soluble in alcohol and ether. Slightly soluble in water.
Beilstein
775913
GHS危害和防范说明
GHS符号
Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
安全信息
危险类别
36/37/38
Irritating to eyes, respiratory system and skin.
安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RTECS
DG2900000
TSCA
是
