应用
4-Iodobenzoyl chloride is employed in the preparation of pyrroles by reaction with imines and acetylenes mediated by isocyanides using palladium catalysis. It is also used in the preparation of N-(1-benzylpyrrolidin-3-yl)arylbenzamides, potential human dopamine D4 antagonists. Further, it is used to prepare [2]rotaxane monomer and poly[2] rotaxane. In addition to this, it is important in the modification of poly(allylamine) in order to make the polymer X-ray visible.
备注
Moisture sensitive. Incompatible with strong bases and water.
基本信息
MDL
MFCD00001058
EINECS
216-974-7
分子式
C7H4ClIO
分子量
266.47
熔点
61-65°
沸点
120-121°/1mm
闪点
>110°(230°F)
灵敏度
Moisture Sensitive. Light Sensitive. Ambient temperatures.
形态
Crystalline powder
溶解性
Soluble in toluene and benzene.
Beilstein
774718
GHS危害和防范说明
GHS符号
Hazard Statements
H314-H318
Causes severe skin burns and eye damage.Causes serious eye damage.
Precautionary Statements
P280-P305+P351+P338-P309-P310
Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF exposed or if you feel unwell:Immediately call a POISON CENTER or doctor/physician.
安全信息
危险等级
8
包装组
III
危险类别
34
Causes burns.
安全等级
26-36/37/39-45
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
欧盟危险品标志
TSCA
是