应用
Hypoxanthine, is used as a marker for energy perturbation in hypoxia/ ischemia. The compound has been used in studies as in indicator, along with uric acid and allantoin , of in vivo free radical reactions. It has been also used in DNA studies to investigate the destabilizing effect it has on DNA duplexes containing hypoxanthine as a base, in a gas phase versus a liquid phase. Hypoxanthine has also been used in studies along with 8-oxoguanine nucleotides to investigate their interaction with human DNA pol ?￥ (DNA polymerase alpha) and DNA polymerase I from Bacillus stearothermophilus. It is also used as a pharmaceutical intermediate.
备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible to Strong oxidizing agents. Stable under recommended storage conditions. Sterilize by filtration through a 0.22 μm filter.
基本信息
MDL
MFCD00005725
EINECS
200-697-3
分子式
C5H4N4O
分子量
136.11
熔点
>300°
灵敏度
Keep Cold.
形态
Powder
溶解性
It does not mix appreciably with water (1:1400). Small octahedra crystals from water.
Beilstein
5811
Merck
14,4869
安全信息
RTECS
UP0791000
TSCA
是
