应用
(R)-(+)-3-Hydroxypyrrolidine is used in the enantioselective addition of diethylzinc to aromatic aldehydes leading to optically active secondary alcohols. Also used to prepare-κ-opioid receptor agonists.
备注
Store under inert gas. It is sensitive to moisture. Store in a cool, dry conditions in well sealed containers. It is hygroscopic and sensitive to air. Incompatible with oxidizing agents.
基本信息
MDL
MFCD00145220
分子式
C4H9NO
分子量
87.12
熔点
15°
沸点
108-110°/8mm
闪点
>110°(230°F)
密度
1.048
折射率
1.4900
灵敏度
Air Sensitive. Hygroscopic. Ambient temperatures.
形态
Liquid
溶解性
Soluble in water and methanol.
Beilstein
5376132
GHS危害和防范说明
GHS符号
Hazard Statements
H315-H319
Causes skin irritation.Causes serious eye irritation.
Precautionary Statements
P280a-P264-P305+P351+P338-P321-P332+P313-P337+P313
Wear protective gloves and eye/face protection.Wash thoroughly after handling.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Specific treatment (see label).If skin irritation occurs: Get medical advice/attention.If eye irritation persists: Get medical advice/attention.
安全信息
危险类别
36/38
Irritating to eyes and skin.
安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
TSCA
否