应用
Hydroxylamine is a reactant used for the preparation of hydroxyaminoguanidines which are anti-cancer agents, carboxamide derivatives of ofloxacin and human immunodeficiency virus (HIV) integrase inhibitors. It reacts with chlorosulfonic acid to give hydroxylamine-O-sulfonic acid, a useful reagent in the synthesis of caprolactam. It is commonly used as a reducing agent in myriad of organic and inorganic reactions. It acts as an antioxidant for fatty acids. It is widely used to prepare oximes, an important functional group.
备注
It can violently decompose at elevated temperatures. May be shock-sensitive if dry. Do not heat over 500C. Incompatible with bases, oxidizing agents, nitrates, nitrites, heavy metals, rubber, metals, epoxides and polyester.
基本信息
MDL
MFCD00044522
EINECS
232-259-2
分子式
H3NO
分子量
33.03
熔点
7°
沸点
107-114°
闪点
None
密度
1.120
折射率
1.3940
灵敏度
Ambient temperatures.
形态
Liquid
溶解性
Miscible with water, liquid ammonia and methanol. Slightly miscible with ether, benzene, carbon disulfide and chloroform.
Beilstein
1098214
Merck
14,4828
GHS危害和防范说明
GHS符号
Hazard Statements
H302-H313-H315-H318-H317-H351-H335-H373-H400
Harmful if swallowed.May be harmful in contact with skin.Causes skin irritation.Causes serious eye damage.May cause an allergic skin reaction.Suspected of causing cancer.May cause respiratory irritation.May cause damage to organs through prolonged or repeated exposure.Very toxic to aquatic life.
Precautionary Statements
P260-P201-P280-P305+P351+P338-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray.Obtain special instructions before use.Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
安全信息
UN#
UN3266
危险等级
8
包装组
III
危险类别
21/22-37/38-40-41-43-48/22-50
Harmful in contact with skin and if swallowed.Irritating to respiratory system and skin.Limited evidence of a carcinogenic effect.Risk of serious damage to eyes.May cause sensitization by skin contact.Harmful: danger of serious damage to health by prolonged exposure if swallowed.Very toxic to aquatic organisms.
安全等级
26-36/37/39-46-61
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.If swallowed, seek medical advice immediately and show this container or label.Avoid release to the environment. Refer to special instructions/safety data sheets.
欧盟危险品标志
RTECS
NC2975000
TSCA
是