应用
Histamine dihydrochloride has been shown to activate nitric oxide synthetase and suppress or inhibit the generation of reactive oxygen species (ROS). Inhibition of ROS by histamine dihydrochloride allows activation of T cells and NK cells by IL-2. In a rat model, histamine dihydrochloride suppressed ROS generated by Kupffer cells through the H2 histamine receptor. It is a potent vasodilator and endogenous histamine receptor agonist.

备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents. Store away from oxidizing agents. Store at 4?°C.

基本信息

MDL
MFCD00012703

EINECS
200-298-4

分子式
C₅H₉N₃?2HCl

分子量
184.07

熔点
245-249°

灵敏度
Ambient temperatures.

溶解性
Very soluble in water and methanol. Soluble in ethanol.

Beilstein
3624116

Merck
14,4719

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H334-H317-H335
Causes skin irritation.Causes serious eye irritation.May cause allergy or asthma symptoms or breathing difficulties if inhaled.May cause an allergic skin reaction.May cause respiratory irritation.

Precautionary Statements
P284-P261-P280a-P305+P351+P338-P405-P501a
Wear respiratory protection.Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38-42/43
Irritating to eyes, respiratory system and skin.May cause sensitization by inhalation and skin contact.

安全等级
22-24-26-37-45-60
Do not breathe dust.Avoid contact with skin.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).This material and its container must be disposed of as hazardous waste

欧盟危险品标志

RTECS
MS1575000

TSCA
是