应用
Harmine, inhibits the Wnt signaling pathway in a cell-specific manner. Down-regulates inflammatory gene expression (TNF-α, IL-1β, iNOS). Reversibly inhibits MAO-A (monoamine oxidase A) but has no effect on MAO-B. Harmine is an inhibitor of Dyrk1A, Dyrk2 and Dyrk3.
备注
Keep container tightly closed in a dry and well-ventilated place. Keep away from oxidizing agents. Stable under recommended storage conditions.
基本信息
MDL
MFCD00004958
EINECS
207-131-4
分子式
C13H12N2O
分子量
212.25
熔点
262-266°
灵敏度
Ambient temperatures.
形态
Powder
溶解性
Soluble in DMSO (100 mM), DMF (～1.5 mg/ml), ethanol (～1.5 mg/ml), and PBS (pH 7.2, ～0.25 mg/ml). Insoluble in water.
Beilstein
178813
Merck
14,4616
GHS危害和防范说明
GHS符号
Hazard Statements
H302-H332-H319
Harmful if swallowed.Harmful if inhaled.Causes serious eye irritation.
Precautionary Statements
P280h-P305+P351+P338
Wear protective gloves/clothing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
安全信息
危险等级
6.1
包装组
III
危险类别
20/22-36
Harmful by inhalation and if swallowed.Irritating to eyes.
安全等级
9-26-36-60
Keep container in a well-ventilated place.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing.This material and its container must be disposed of as hazardous waste
欧盟危险品标志
RTECS
UV0175000
TSCA
否
