应用
Ethyl propiolate is used as a precursor in the preparation of substituted anthraquinones and pyrazolo[1,5-a]pyridine, which exhibits anti-inflammatory activity. Further, it is employed in the synthesis of benzene-1,2,3,5-tetracarboxylates promoted by triphenylphosphine. Its halogenated derivatives are used as a substrate for direct, asymmetric alkynylation of cyclic beta-ketoesters using chiral phase-transfer catalysts.
备注
Incompatible with oxidizing agents, bases and acids.
基本信息
MDL
MFCD00009184
EINECS
210-795-8
分子式
C5H6O2
分子量
98.10
熔点
9°
沸点
118-120°
闪点
23°(73°F)
密度
0.963
折射率
1.4120
灵敏度
Keep Cold.
形态
Liquid
溶解性
Miscible with alcohol.
Beilstein
878250
GHS危害和防范说明
GHS符号
Hazard Statements
H226-H315-H319-H335
Flammable liquid and vapour.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements
P210-P261-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.Avoid breathing dust/fume/gas/mist/vapours/spray.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
安全信息
危险等级
3
包装组
III
危险类别
10-36/37/38
Flammable.Irritating to eyes, respiratory system and skin.
安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste
TSCA
否