应用
Ethyl potassium malonate is used as a competitive inhibitor of the enzyme succinate dehydrogenase. It acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation. Further, it reacts with aryl nitriles to prepare beta-amino acrylates in the presence of zinc chloride and a catalytic amount of H??nig's base. In addition to this, it serves as an intermediate for the preparation of ethyl tert-butyl malonate.
备注
Hygroscopic. Incompatible with strong oxidizing agents.
基本信息
MDL
MFCD00035603
EINECS
228-156-7
分子式
C5H7KO4
分子量
170.21
熔点
ca 200° dec.
灵敏度
Hygroscopic. Ambient temperatures.
形态
Powder
溶解性
Soluble in water.
Beilstein
3721682
安全信息
TSCA
否