应用
2,2-Difluoroacetophenone acts as an intermediate in the preparation of various substances such as pharmaceuticals. Further, it is used in the one-pot synthesis of difluoromethylated arenes from aryl chlorides and bromides. In addition to this, it undergoes reduction with (-)-diisopinocampheylchloroborane chloride to get R-alcohols of purity 85% ee.
备注
Incompatible with strong oxidizing agents and strong acids.
基本信息
MDL
MFCD06246879
分子式
C8H6F2O
分子量
156.13
熔点
48-50°
沸点
53-54°/12mm
折射率
1.4955
灵敏度
Ambient temperatures.
形态
Liquid
溶解性
Immiscible with water.
GHS危害和防范说明
GHS符号
Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements
P280g-P305+P351+P338
Wear protective gloves.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
安全信息
危险类别
36/37/38
Irritating to eyes, respiratory system and skin.
安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
TSCA
否
