应用
Diethyl malonate is used in organic synthesis for the preparation of alpha-aryl malonates, mono-substituted and di-substituted acetic acid, barbiturates and artificial flavorings. It is also involved in the synthesis of pharmaceuticals like chloroquine, butazolidin and barbital. It acts as intermediate in the synthesis of vitamin B1, vitamin B6, non-steroidal anti-inflammatory agents agrochemicals and perfumes. In Knoevenagel condensation reaction, it reacts with benzaldehyde to get diethyl benzylidenemalonate.
备注
Incompatible with acids, bases, oxidizing agents and reducing agents.
基本信息
MDL
MFCD00009195
EINECS
203-305-9
分子式
C7H12O4
分子量
160.17
熔点
-50°
沸点
198-200°
闪点
90°(194°F)
密度
1.055
折射率
1.4140
灵敏度
Ambient temperatures.
形态
Liquid
溶解性
Miscible with ethyl alcohol, ether, chloroform and benzene. Slightly miscible with water.
Beilstein
774687
Merck
14,3823
GHS危害和防范说明
Hazard Statements
H227
Combustible liquid.
Precautionary Statements
P210e-P280a-P370+P378a-P403+P235-P501a
Wear protective gloves and eye/face protection.In case of fire: Use for extinction: CO2, powder or water spray.Store in a well-ventilated place. Keep cool.Dispose of contents/container in accordance with local/regional/national/international regulations.
安全信息
RTECS
OO0700000
TSCA
是
