应用
2,4-Dibromothiazole is applied as a building block in a synthesis of Melithiazole C employing a highly (E)-selective cross-metathesis between the derived 4-vinylthiazole and a dienote side-chain. It is also used as an intermediate in the preparation of various 2,4-disubstituted thiazole derivatives with biologically active properties such as survival motor neuron (SMN) protein modulators.
备注
Air sensitive. Incompatible with oxidizing agents.
基本信息
MDL
MFCD01318994
分子式
C3HBr2NS
分子量
242.92
熔点
80-84°
灵敏度
Store under Nitrogen. Ambient temperatures.
形态
Solid
GHS危害和防范说明
GHS符号
Hazard Statements
H302-H315-H318-H335
Harmful if swallowed.Causes skin irritation.Causes serious eye damage.May cause respiratory irritation.
Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
安全信息
危险类别
22-37/38-41
Harmful if swallowed.Irritating to respiratory system and skin.Risk of serious damage to eyes.
安全等级
26-36/37/39-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.This material and its container must be disposed of as hazardous waste
欧盟危险品标志
TSCA
否