应用
Cyclopropanecarboxaldehyde reacts with Grignard or organolithium reagents to give the expected secondary alcohols. These are susceptible to ring opening in the presence of HBr, providing stereoselective access to homoallylic bromides. It is also used in the synthesis of eta(2)-enonenickel complexes by reacting with [Ni(cod)(2)] (cod = 1,5-cyclooctadiene) and PBu(3) and to prepare a cyclopropylidene tetralone which underwent an enantioselective palladium-catalyzed [3+2] TMM cycloaddition providing a chiral spiro-fused cyclopentene.
备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Recommended storage temperature is 2 - 8°C. It is sensitive to air.
基本信息
MDL
MFCD00012261
EINECS
000-000-0
分子式
C4H6O
分子量
70.09
沸点
98-101°
闪点
7°(44°F)
密度
0.938
折射率
1.4298
灵敏度
Air Sensitive. Store under Argon. Ambient temperatures.
形态
Liquid
溶解性
Soluble in water.
Beilstein
906781
GHS危害和防范说明
GHS符号
Hazard Statements
H225-H314-H318
Highly flammable liquid and vapour.Causes severe skin burns and eye damage.Causes serious eye damage.
Precautionary Statements
P210-P260h-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.Keep away from heat/sparks/open flames/hot surfaces. - No smoking.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
安全信息
危险等级
3
包装组
II
危险类别
11-34
Highly flammable.Causes burns.
安全等级
9-16-20-23-26-36/37/39-45-60
Keep container in a well-ventilated place.Keep away from sources of ignition - No smoking.When using do not eat or drink.Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).This material and its container must be disposed of as hazardous waste
欧盟危险品标志
RTECS
GZ1005000
TSCA
是
