应用
5-Chlorothiophene-2-sulfonyl chloride is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuffs. It is used in the preparation of Notch-1-sparing γ-secretase inhibitors for the treatment of Alzheimer's disease.
备注
Moisture Sensitive. Store at 4?°C. Incomaptible with oxidizing agents and bases.
基本信息
MDL
MFCD00051667
EINECS
700-248-6
分子式
C4H2Cl2O2S2
分子量
217.09
沸点
117-120°/14mm
闪点
>110°(230°F)
密度
1.623
折射率
1.5860
灵敏度
Keep Cold. Moisture Sensitive. Store under Nitrogen.
形态
Liquid
溶解性
Not miscible in water.
Beilstein
130710
GHS危害和防范说明
GHS符号
Hazard Statements
H314-H318
Causes severe skin burns and eye damage.Causes serious eye damage.
Precautionary Statements
P260h-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
安全信息
危险等级
8
包装组
III
危险类别
34
Causes burns.
安全等级
20-23-26-36/37/39-45-60
When using do not eat or drink.Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).This material and its container must be disposed of as hazardous waste
欧盟危险品标志
TSCA
否
