应用
Chloromethyl methyl sulfide is used as a methylene transfer reagent for iron(II) mediated cyclopropanation and for carbonyl and aromatic compounds. It protects alcohols as their methylthiomethyl (MTM) ethers by reaction, e.g. with NaH/NaI in DME. It is also used for the preparation of MTM esters of carboxylic acids, e.g. by treatment of the K salt of the acid in the presence of NaI and 18-crown-6 and for reaction with cyclopentadienyl iron dicarbonyl dimer in the formation of an iron-containing methylene transfer agent.
备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Recommended storage temperature: 2 - 8?°C. Incompatible with strong oxidizing agents.
基本信息
MDL
MFCD00000923
EINECS
219-148-4
分子式
CH3SCH2Cl
分子量
96.58
沸点
104-105°
闪点
17°(62°F)
密度
1.160
折射率
1.4980
灵敏度
Keep Cold. Moisture Sensitive. Store under Nitrogen.
形态
Liquid
溶解性
Soluble in acetonitrile, ether and dichloromethane. Insoluble in water.
Beilstein
1730851
GHS危害和防范说明
GHS符号
Hazard Statements
H225-H315-H319-H335
Highly flammable liquid and vapour.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements
P210-P261-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.Avoid breathing dust/fume/gas/mist/vapours/spray.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
安全信息
危险等级
3
包装组
II
危险类别
11-36/37/38
Highly flammable.Irritating to eyes, respiratory system and skin.
安全等级
9-16-26-33-37-60
Keep container in a well-ventilated place.Keep away from sources of ignition - No smoking.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Take precautionary measures against static discharges.Take precautionary measures against static discharges.This material and its container must be disposed of as hazardous waste
欧盟危险品标志
RTECS
WQ3700000
TSCA
否
