应用
2-Butynoic acid is used as an intermediate in organic synthesis and pharmaceuticals. It is used as a synthon in various reactions, which includes cylcoalkylation of phenols to flavones and chromones. It is involved in the cyclization of gamma-butyrolactones. It is also used in the synthesis of Z-trisubstituted olefins through µ-alkylation. It plays an important role in the preparation of chirally pure 1,2,3,4-tetrahydroisoquinoline analogs, which finds application as anti-cancer agents.
备注
Store in a cool place. Incompatible with strong oxidizing agents, strong bases and strong reducing agents.
基本信息
MDL
MFCD00004363
EINECS
209-695-7
分子式
C4H4O2
分子量
84.07
熔点
75-79°
沸点
200-203°
密度
0.964
灵敏度
Keep Cold.
形态
Crystalline powder
溶解性
Soluble in water. Slightly soluble in methanol and chloroform.
Beilstein
1740205
GHS危害和防范说明
GHS符号
Hazard Statements
H314-H318
Causes severe skin burns and eye damage.Causes serious eye damage.
Precautionary Statements
P280-P305+P351+P338-P308+P313
Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF exposed or concerned: Get medical advice/attention.
安全信息
危险等级
8
包装组
II
危险类别
34
Causes burns.
安全等级
26-36/37/39-45
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
欧盟危险品标志
TSCA
是
