应用
3-Bromo-1-trimethylsilyl-1-propyne is used in the preparation of tetrahydroisoquinoline-3-carboxylic acid derivatives. It acts as a propargylating agent and used for the alkylation of dianion of beta-keto esters at gamma-carbon. It plays an important role in the synthesis of allenic alcohols and terminal conjugated enynes.
备注
Store in cool place. Incompatible with strong oxidizing agents.
基本信息
MDL
MFCD00134460
分子式
C6H11BrSi
分子量
191.14
沸点
44-45°/2mm
闪点
63°(145°F)
密度
1.17
折射率
1.483
灵敏度
Ambient temperatures.
形态
Liquid
溶解性
Immiscible with water.
Beilstein
2037650
GHS危害和防范说明
GHS符号
Hazard Statements
H227-H315-H319-H335
Combustible liquid.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements
P210e-P261-P280a-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
安全信息
危险类别
36/37/38
Irritating to eyes, respiratory system and skin.
安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
TSCA
否
