应用
It is a reactant for preparation of anilinopyrimidinesulfonamides as potential anticancer agents, synthesis of inhibitors of the hypoxia inducible factor pathway. It participates in the preparation of hydroxy-sulfonyl-piperidinyl butyramides as HDAC inhibitors and potential antitumors and is also involved in palladium-catalyzed desulfitative C-arylation.
备注
Store at room temperature. Keep away from moisture, bases and oxidizing agents.
基本信息
MDL
MFCD00078658
EINECS
216-609-1
分子式
C12H9ClO2S
分子量
252.72
熔点
112-117°
沸点
200-205°/6mm
灵敏度
Moisture Sensitive. Store under Nitrogen. Ambient temperatures.
形态
Powder
溶解性
Reacts with water.
Beilstein
2694373
GHS危害和防范说明
GHS符号
Hazard Statements
H314-H318
Causes severe skin burns and eye damage.Causes serious eye damage.
Precautionary Statements
P260h-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
安全信息
危险等级
8
包装组
II
危险类别
14-34
Reacts violently with water.Causes burns.
安全等级
8-20-26-30-36/37/39-45-60
Keep container dry.When using do not eat or drink.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Never add water to this product.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).This material and its container must be disposed of as hazardous waste
欧盟危险品标志
TSCA
否