应用
Benzyl 2,2,2-trichloroacetimidate is used for the acid-catalyzed benzylation of hydroxy groups. It acts as reagent during the synthesis of funiculosin dimethyl ether and (S)-3-(benzyloxy)-2-methylpropanal. It can also be used for mild esterification of carboxylic acids in the presence of a catalytic amount of BF3 etherate.
备注
Moisture and light sensitive. Incompatible with strong oxidizing agents and strong acids.
基本信息
MDL
MFCD00000805
EINECS
617-271-1
分子式
C9H8Cl3NO
分子量
252.53
沸点
110-114°/0.5mm
闪点
>110°(230°F)
密度
1.356
折射率
1.5450
灵敏度
Keep Cold. Moisture Sensitive. Store under Nitrogen.
形态
Liquid
溶解性
Miscible with cyclohexane/dichloromethane.
Beilstein
2525375
GHS危害和防范说明
GHS符号
Hazard Statements
H302-H315-H319-H335
Harmful if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
安全信息
危险类别
22-36/37/38
Harmful if swallowed.Irritating to eyes, respiratory system and skin.
安全等级
23-26-36/37-60
Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.This material and its container must be disposed of as hazardous waste
欧盟危险品标志
TSCA
否
