应用
Benzyl isocyanate, is used as a protected ammonia equivalent in the stereo selective ring-opening of chiral 2,3-epoxy alcohols (from Sharpless asymmetric epoxidation). The key step in the sequence involves intramolecular cyclization of the carbamate intermediate. It is also used in a multicomponent, stereospecific synthesis of 1,3-oxazinane-2,4-diones employing an Al-salph complex.
备注
Moisture& heat Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from alcohols, amines.
基本信息
MDL
MFCD00009701
EINECS
221-640-9
分子式
C8H7NO
分子量
133.15
沸点
53-54°/0.8mm
闪点
43°(109°F)
密度
1.078
折射率
1.5250
灵敏度
Keep Cold. Moisture Sensitive.
形态
Liquid
溶解性
It hydrolyzes with water.
Beilstein
636508
GHS危害和防范说明
GHS符号
Hazard Statements
H226-H301-H330-H315-H319-H334-H335
Flammable liquid and vapour.Toxic if swallowed.Fatal if inhaled.Causes skin irritation.Causes serious eye irritation.May cause allergy or asthma symptoms or breathing difficulties if inhaled.May cause respiratory irritation.
Precautionary Statements
P301+P310a-P303+P361+P353-P304+P340-P305+P351+P338-P320-P330-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Specific treatment is urgent (see label).Rinse mouth.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
安全信息
危险等级
6.1
包装组
II
危险类别
10-23/25-36/37/38-42
Flammable.Toxic by inhalation and if swallowed.Irritating to eyes, respiratory system and skin.May cause sensitization by inhalation.
安全等级
23-26-36/37-45
Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
TSCA
否
