应用
Benzyl carbazate is used as a reagent for preparation of benzyloxycarbonyl (Z, Cbz) hydrazides of carboxylic acids, particularly N-protected amino acids. Subsequent hydrogenolysis gives the hydrazide which can be converted to the azide for coupling with a further amino acid residue by the azide method. It is also used in the preparation of simple acyl or sulfonyl hydrazides avoiding diacylation.

备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Handle under inert gas. Protect from moisture. Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00041890

EINECS
226-230-3

分子式
C₈H₁₀N₂O₂

分子量
166.18

熔点
66-70°

灵敏度
Ambient temperatures.

形态
Crystalline

溶解性
Soluble in water (slightly), methanol and DMSO.

Beilstein
1952982

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H318-H335
Causes skin irritation.Causes serious eye damage.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
37/38-41
Irritating to respiratory system and skin.Risk of serious damage to eyes.

安全等级
26-37/39
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable gloves and eye/face protection.

RTECS
MV1724950

TSCA
是