应用
1,4-Benzodioxan-6-carboxaldehyde finds its uses as building block in the synthesis of tetrahydroisoquinolinones, in the preparation of benzofuran analog, a potential inhibitor of CAMP-specific phosphodiesterase type IV, in the synthesis of (5Z)-5-(2,3-dihydro-1,4-benzodioxan-6-ylmethylene)-1-methyl-2-thioxoimidazolidin-4-one. It was screened as a fragment for inhibitors of PDEA using enthalpy arrays and X-ray crystallography. 1,4-Benzodioxane-6-carboxaldehyde have also been used as an intermediate in the synthesis of a new class of Dopamine D3 and D4 receptor antagonists.
备注
Store away from air, oxidizing agents and bases. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
基本信息
MDL
MFCD00010092
EINECS
249-763-3
分子式
C9H8O3
分子量
164.16
熔点
48-52°
沸点
104-106°/15mm
闪点
>110°(230°F)
灵敏度
Air Sensitive. Ambient temperatures.
形态
Powder
溶解性
Solubility in methanol is almost transparent.
安全信息
TSCA
否