应用
Biospecific adsorption of carbonic anhydrase to self-assembled monolayers of alkanethiolates that present benzenesulfonamide groups on gold. Biospecific binding of carbonic anhydrase to mixed sams presenting benzenesulfonamide ligands led to a model system for studying lateral steric effects. Benzenesulfonamide modifications at c-7 of ciprofloxacin change its primary target instreptococcus pneumoniae from topoisomerase iv to gyrase. Polar substitutions in the benzenesulfonamide ring of celecoxib afford a potent 1,5-diarylpyrazole class of COX-2 inhibitors.
备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
基本信息
MDL
MFCD00007930
EINECS
202-637-1
分子式
C6H7NO2S
分子量
157.19
熔点
151-154°
闪点
250°(482°F)
灵敏度
Ambient temperatures.
形态
Crystalline powder
溶解性
Soluble in methanol (25 mg/ml), and water (4.3 mg/ml at 16°C).
Beilstein
1100566
GHS危害和防范说明
GHS符号
Hazard Statements
H302
Harmful if swallowed.
Precautionary Statements
P280f
Wear protective clothing.
安全信息
危险类别
22
Harmful if swallowed.
安全等级
36-60
Wear suitable protective clothing.This material and its container must be disposed of as hazardous waste
欧盟危险品标志
RTECS
DA9380000
TSCA
是