位置:首页 > 品牌 > 阿法埃莎 >

Azelaic Acid

壬二酸

品牌
Alfa Aesar
CAS
123-99-9
货号
A17271
规格纯度
tech. 80%
参考价格
550 *本价格含增值税费
促销
数量
-+
产品介绍:

应用
It is applied in organic synthesis, lacquers, polyester adhesives, and urethane elastomers. Azelaic acid directly inhibits kallikrein 5 (KLK5), down regulating expression of KLK5, toll-like receptor 2 (TLR 2), and cathelicidin, and suppresses activity of serine proteases in vitro, in vivo, and in clinical settings. In PUFA-treated fibroblasts, azelaic acid decreases generation of ROS and up regulates expression of antioxidative enzymes, inhibiting cell damage; agonist activity at PPAR? is thought to drive these effects. Azelaic acid also inhibits proliferation of melanocytes. This compound displays antiacne and anticancer potential as well, inhibiting the proliferation of cutaneous melanoma due to suppression of mitochondrial oxidoreductive activity and DNA synthesis. It is a component of a number of hair and skin conditioners. Azelaic acid is used to treat mild to moderate acne, both comedonal acne and inflammatory acne. It is used in lubrication and plasticizers.

备注
Store away from strong oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

基本信息

MDL
MFCD00004432

EINECS
204-669-1

分子式
HOOC(CH2)7COOH

分子量
188.22

熔点
ca 102°

沸点
286°/100mm

闪点
215°(419°F)

密度
1.225

灵敏度
Ambient temperatures.

形态
Crystalline

溶解性
Soluble in water at 20°C 2.4 g/L. Soluble in ethanol (5%), DMSO, methanol (70 mg/ml), and alcohol.

Beilstein
1101094

Merck
14,905

安全信息

RTECS
CM1980000

TSCA

阿法埃莎

推荐产品
| 首页 | 联系我们 | 会员服务 | 广告服务 | 友情链接 |
版权所有 CopyRight © 2008-2024 粤ICP备08119708号