应用
3-Aminocrotononitrile reacts with ferrocenyl-1,2-enones to form ferrocenyl pyridines. It undergoes diazotization coupling reaction with p-substituted anilines to give 2-arylhydrazone-3-ketimino-butyronitriles.3-Aminocrotononitrile, (E)+(Z), is used in reaction with aryldiazonium salts gave, instead of the expected triazene, 2-arylhydrazono-3-ketobutyronitrile by electrophilic attack at the ?-carbon and hydrolysis of the resulting imine. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. 3-Aminocrotononitrile was used as bisnucleophilic reagent which on cyclocondensation with hexafluoroacetone(ethoxycarbonylimine) forms bis(trifluoromethyl)pyrimidinones.
备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from oxidizing agents.
基本信息
MDL
MFCD00008071
EINECS
214-266-2
分子式
C4H6N2
分子量
82.11
熔点
ca 70-75°
沸点
120°/4mm
闪点
154°(309°F)
灵敏度
Keep Cold.
形态
Crystalline flakes or powder
溶解性
Very soluble in water, soluble in ethanol.
Beilstein
1719815
GHS危害和防范说明
GHS符号
Hazard Statements
H302-H319-H317
Harmful if swallowed.Causes serious eye irritation.May cause an allergic skin reaction.
Precautionary Statements
P261-P280-P305+P351+P338-P302+P352-P321-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF ON SKIN: Wash with plenty of soap and water.Specific treatment (see label).Dispose of contents/container in accordance with local/regional/national/international regulations.
安全信息
危险等级
6.1
包装组
III
危险类别
20/22-36/37
Harmful by inhalation and if swallowed.Irritating to eyes and respiratory system.
安全等级
26-36/37/39
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.
欧盟危险品标志
TSCA
是
