应用
(Acetylmethylene)triphenylphosphorane is used as a Wittig reagent in synthetic chemistry, especially for the synthesis of functionalized pyrrolidines and cyclobutanones. It plays as a vital role in asymmetric allylboration for enantioselective synthesis of (+)-awajanomycin.It is also employed as a reactant in the preparation of 1,2-dioxanes with antitrypanosomal activity. Further, it is used in the preparation of amphibian pyrrolizidine alkaloids through allylic aminations and silicon-containing acyclic dienone musk odorants. In addition to this, it is involved in Domino Suzuki/Heck coupling reactions to prepare fluorenylidenes.
备注
Air sensitive. Incompatible with strong oxidizing agents.
基本信息
MDL
MFCD00008774
EINECS
215-878-2
分子式
C21H19OP
分子量
318.36
熔点
204-209°
灵敏度
Keep Cold. Air Sensitive.
形态
Crystalline powder
溶解性
Soluble in chloroform. Slightly soluble in methanol.
Beilstein
750077
安全信息
RTECS
UC3900000
TSCA
否
