应用
3-(Trimethylsilyl)propargyl alcohol is used as a reagent to synthesize Isbogrel, a Thromboxane A 2 (TXA 2) synthase inhibitor and also a TXA 2 receptor antagonist that has potential to treat asthma.

备注
Moisture Sensitive. Store away from moisture and oxidizing agents. Protect from heat. Store under dry inert gas. Protect from humidity and water. Incompatible with oxidizing agents, heat and moisture.

基本信息

MDL
MFCD00002913

EINECS
226-094-5

分子式
C₆H₁₂OSi

分子量
128.25

沸点
170-172°

闪点
66°(150°F)

密度
0.865

折射率
1.4510

灵敏度
Keep Cold. Moisture Sensitive.

形态
Liquid

溶解性
Not miscible with water.

Beilstein
1902505

GHS危害和防范说明

GHS符号

Hazard Statements
H227-H301-H315-H319-H335
Combustible liquid.Toxic if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280h-P305+P351+P338-P309-P310
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves/clothing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF exposed or if you feel unwell:Immediately call a POISON CENTER or doctor/physician.

安全信息

危险类别
25-36/37/38
Toxic if swallowed.Irritating to eyes, respiratory system and skin.

安全等级
23-26-36/37-45
Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

TSCA
是