应用
1-(Trimethylsilyl)imidazole acts as a silylating agent for alcohols, carbohydrates and 1,3-dicarbonyl compounds. It is a derivatization reagent used for selective silylation of hydroxyl groups and carboxylic acid without affecting the amino group. It employed as an intermediate for the synthesis of imidazole derivatives. It plays an essential role to synthesize polysubstituted chiral spirotetrahydropyrans. It is also used in the quantification of pintol after derivatization by gas chromatography/ mass spectrometry.
备注
Moisture and light sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents and strong acids.
基本信息
MDL
MFCD00005280
EINECS
242-040-3
分子式
C6H12N2Si
分子量
140.26
熔点
-42°
沸点
212°
闪点
18°(64°F)
密度
0.956
折射率
1.4765
灵敏度
Moisture Sensitive. Ambient temperatures.
形态
Liquid
溶解性
Miscible with most common organic solvents. It decomposes in water.
Beilstein
606148
GHS危害和防范说明
GHS符号
Hazard Statements
H225-H315-H319-H335
Highly flammable liquid and vapour.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements
P210-P261-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.Avoid breathing dust/fume/gas/mist/vapours/spray.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
安全信息
危险等级
3
包装组
II
危险类别
11-36/37/38
Highly flammable.Irritating to eyes, respiratory system and skin.
安全等级
16-26-33-37
Keep away from sources of ignition - No smoking.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Take precautionary measures against static discharges.
欧盟危险品标志
RTECS
NI8700000
TSCA
是
