应用
Triisopropylsilyl trifluoromethanesulfonate is used as a reagent for the introduction of triisopropylsilyl(TIPS) group in organic synthesis. It is involved in the synthesis of 2-substituted benzothiopyran-4-ones and silyloxy acetylenes. As a protecting group in organic synthesis, it is utilized especially for the protection of primary amines. Furthermore, it plays an important role in Takahashi Taxol total synthesis or for chemical glycosylation reactions.
备注
Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong bases and strong oxidizing agents. Hydrolyzes in water.
基本信息
MDL
MFCD00009913
EINECS
000-000-0
分子式
CF3SO3Si[CH(CH3)2]3
分子量
306.42
沸点
45-46°/0.03mm
闪点
100°(212°F)
密度
1.136
折射率
1.4150
灵敏度
Moisture Sensitive. Ambient temperatures.
形态
Liquid
溶解性
Miscible with chloroform and ethyl acetate.
Beilstein
3591541
GHS危害和防范说明
GHS符号
Hazard Statements
H314-H318
Causes severe skin burns and eye damage.Causes serious eye damage.
Precautionary Statements
P260h-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
安全信息
危险等级
8
包装组
II
危险类别
34
Causes burns.
安全等级
26-36/37/39-45
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
欧盟危险品标志
TSCA
否
