应用
Trifluoromethanesulfonic acid acts as a catalyst for esterification reactions and an acidic titrant in nonaqueous acid-base titration. It is useful in protonations due to the presence of conjugate base triflate is non nucleophilic. It serves as a deglycosylation agent for glycoproteins. In addition, it is a precursor and a catalyst in organic chemistry. It reacts with acyl halides to prepare mixed triflate anhydrides, which are strong acylating agents used in Friedel-Crafts reactions. It acts as a key starting material for the preparation of ethers and olefins by reacting with alcohols as well as to prepare trifluoromethanesulfonic anhydride by dehydration reaction.
备注
Hygroscopic. Incompatible with strong oxidizing agents, strong bases, water and metals.
基本信息
MDL
MFCD00007514
EINECS
216-087-5
分子式
CHF3O3S
分子量
150.07
熔点
-40°
沸点
161-162°
闪点
None
密度
1.708
折射率
1.3270
灵敏度
Hygroscopic. Store under Nitrogen. Ambient temperatures.
形态
Liquid
溶解性
Miscible with water, dimethyl sulfoxide, dimethyl formamide and acetonitrile.
Beilstein
1812100
Merck
14,9676
GHS危害和防范说明
GHS符号
Hazard Statements
H302-H314-H318-H335-H402-H412
Harmful if swallowed.Causes severe skin burns and eye damage.Causes serious eye damage.May cause respiratory irritation.Harmful to aquatic life.Harmful to aquatic life with long lasting effects.
Precautionary Statements
P260h-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.
安全信息
危险等级
8
包装组
II
危险类别
22-34-37-52/53
Harmful if swallowed.Causes burns.Irritating to respiratory system.Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
安全等级
20-23-26-36/37/39-45-60-61
When using do not eat or drink.Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).This material and its container must be disposed of as hazardous wasteAvoid release to the environment. Refer to special instructions/safety data sheets.
欧盟危险品标志
RTECS
PB2771000
TSCA
是
